[解題技巧心得]

 [解題技巧心得]

參考資料
https://www.reddit.com/…/…/8ye6r4/my_writeup_for_step_1_256/

文中說解題善用deductive reasoning演繹法
準備考試就是理解跟背熟FA裡面的fact
考試進去推理,用fact去演繹deductive reasoning

Example: fatty acid synthesis occurs in fat cells. Therefore I’d expect to see high levels of G6PDH there to provide NADPH, which is a cofactor for fatty acid synthase. I would have never immediately made that connection, but I understand the connection based on biochemistry

常識: Fatty acid synthesis在fat cell裡面
讀書知識: 因為Fatty acid synthesis需要NADPH (Kaplan p. 219)
讀書知識: 而NADPH由G6PDH(glucose-6-p dehydrogenase)還原而來(Kaplan p. 209, HMP shunt)
(補充: 所以G6PD deficiency→RBC沒NADPH對抗氧化壓力→hemolytic anemia)
所以演繹結論: fat cell裡面有很多G6PDH, 來提供 G6PDH, 可以完成作用Fatty acid synthesis

所以考試給一個東西
要先想到fat cell 跟哪些生化有關, ok, Fatty acid synthesis
在往下面推, Fatty acid synthesis需要什麼enzyme/cofactor
所以fat cell 裡面應該有這個東西

所以念書死背是沒用的
只背那兩個讀書知識
可能解不了這題
但其實不是因為不會知識,而是推理推論的過程,這也是做很多題目,增加自己準度的重要
只讀書不做題目不行,但沒讀夠書就直接做題目,也會不達標
生化機制,發生的位置非常重要
pentose phosphate pathway就是HMP shunt
FA75有